Wednesday’s game at Littlejohn Coliseum has the No. 13 Clemson Tigers (22-5, 14-2 ACC) matching up with the Notre Dame Fighting Irish (12-15, 6-10 ACC) at 7:00 PM ET. Our computer prediction is a lopsided 79-66 victory, as our model heavily favors Clemson.

Based on our computer prediction, Notre Dame is a good bet to cover the spread, which is listed at 14.5. The two sides are projected to go over the 137.5 over/under.

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Clemson vs. Notre Dame Game Info & Odds

• Date: Wednesday, February 26, 2025
• Time: 7:00 PM ET
• TV: ACC Network
• Live stream: Watch this game on Fubo (Regional restrictions may apply)
• Where: Clemson, South Carolina
• Venue: Littlejohn Coliseum
• Line: Clemson -14.5
• Point total: 137.5
• Moneyline (to win): Clemson -1449, Notre Dame +810

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Clemson vs. Notre Dame Score Prediction

• Prediction:
  Clemson 79, Notre Dame 66

Spread & Total Prediction for Clemson vs. Notre Dame

• Pick ATS: Notre Dame (+14.5)
• Pick OU: Over (137.5)

Clemson’s record against the spread this season is 17-10-0, and Notre Dame’s is 13-14-0. In terms of going over the point total, games involving the Tigers are 14-13-0 and the Fighting Irish are 13-14-0. The two teams average 150.8 points per game, 13.3 more points than this matchup’s total. Clemson has an 8-2 record against the spread while going 9-1 overall over the last 10 games. Notre Dame has gone 2-8 against the spread and 4-6 overall in its last 10 games.

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Clemson Performance Insights

• The Tigers are outscoring opponents by 11.0 points per game with a +297 scoring differential overall. They put up 77.5 points per game (87th in college basketball) and give up 66.5 per contest (43rd in college basketball).
• Clemson averages 32.4 rebounds per game (167th in college basketball) while allowing 29.7 per contest to its opponents. It outrebounds opponents by 2.7 boards per game.
• Clemson connects on 9.2 three-pointers per game (56th in college basketball) while shooting 38.8% from deep (11th in college basketball). It is making 2.0 more threes per contest than its opponents, who drain 7.2 per game while shooting 32.5%.
• The Tigers’ 102.2 points per 100 possessions on offense rank 43rd in college basketball, and the 87.7 points they allow per 100 possessions rank 53rd in college basketball.
• Clemson has committed 10.1 turnovers per game (69th in college basketball action), 2.4 fewer than the 12.5 it forces on average (88th in college basketball).

Notre Dame Performance Insights

• The Fighting Irish outscore opponents by 1.4 points per game (posting 73.3 points per game, 206th in college basketball, and giving up 71.9 per contest, 184th in college basketball) and have a +38 scoring differential.
• The 31.2 rebounds per game Notre Dame accumulates rank 234th in college basketball, 2.6 more than the 28.6 its opponents collect.
• Notre Dame connects on 7.9 three-pointers per game (158th in college basketball) at a 36.2% rate (67th in college basketball), compared to the 7.6 its opponents make, shooting 32.2% from beyond the arc.
• Notre Dame and its opponents have been mostly even in the turnover battle. The Fighting Irish commit 10.3 per game (88th in college basketball) and force 9.8 (323rd in college basketball).

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