Sunday’s contest features the Louisville Cardinals (19-6, 12-2 ACC) and the Notre Dame Fighting Irish (11-13, 5-8 ACC) clashing at Purcell Pavilion (on February 16) at 8:00 PM ET. This matchup, according to our computer prediction, will result in a 78-69 win for Louisville.

According to our computer prediction, Louisville is projected to cover the spread (6.5) versus Notre Dame. The two teams are projected to go over the 143.5 over/under.

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Louisville vs. Notre Dame Game Info & Odds

• Date: Sunday, February 16, 2025
• Time: 8:00 PM ET
• TV: ACC Network
• Live stream: Watch this game on Fubo (Regional restrictions may apply)
• Where: South Bend, Indiana
• Venue: Purcell Pavilion
• Line: Louisville -6.5
• Point total: 143.5
• Moneyline (to win): Louisville -275, Notre Dame +220

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Louisville vs. Notre Dame Score Prediction

• Prediction:
  Louisville 78, Notre Dame 69

Spread & Total Prediction for Louisville vs. Notre Dame

• Pick ATS: Louisville (-6.5)
• Pick OU: Over (143.5)

Louisville is 15-10-0 against the spread this season compared to Notre Dame’s 12-12-0 ATS record. In terms of hitting the over, games involving the Cardinals are 9-16-0 and the Fighting Irish are 11-13-0. The teams score 153.5 points per game, 10.0 more points than this matchup’s total. Louisville is 7-3 against the spread and 9-1 overall over its last 10 contests, while Notre Dame has gone 4-6 against the spread and 4-6 overall.

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Louisville Performance Insights

• The Cardinals outscore opponents by 10.4 points per game (scoring 79.7 points per game to rank 53rd in college basketball while allowing 69.3 per outing to rank 101st in college basketball) and have a +259 scoring differential overall.
• Louisville wins the rebound battle by 6.3 boards on average. It records 36.0 rebounds per game, which ranks 23rd in college basketball, while its opponents grab 29.7 per outing.
• Louisville makes 2.1 more threes per contest than the opposition, 9.9 (29th in college basketball) compared to its opponents’ 7.8.
• The Cardinals’ 101.5 points per 100 possessions on offense rank 54th in college basketball, and the 88.3 points they allow per 100 possessions rank 74th in college basketball.
• Louisville has committed 1.8 fewer turnovers per game than its opponents, averaging 10.8 (129th in college basketball action) while forcing 12.6 (91st in college basketball).

Notre Dame Performance Insights

• The Fighting Irish have a +73 scoring differential, topping opponents by 3.1 points per game. They’re putting up 73.8 points per game, 197th in college basketball, and are allowing 70.7 per contest to rank 147th in college basketball.
• Notre Dame comes out on top in the rebound battle by an average of 3.8 boards. It records 32.2 rebounds per game (176th in college basketball) compared to its opponents’ 28.4.
• Notre Dame makes 8.0 three-pointers per game (149th in college basketball) compared to its opponents’ 7.4. It shoots 36.9% from deep, and its opponents shoot 31.7%.
• Notre Dame has committed 10.2 turnovers per game (74th in college basketball) while forcing 9.7 (327th in college basketball).

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