On Sunday, December 15, 2024 at Ford Field, the Detroit Lions (12-1) are favored by 2.5 points as they battle to keep their 11-game winning streak intact in a matchup with the Buffalo Bills (10-3). The over/under is set at 54.5 points for the contest.

Before the Lions play the Bills, prepare for the matchup by checking out their betting trends and insights.

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Lions vs. Bills Odds, Spread, Over/Under

Check out the odds, spread and over/under for this matchup available at several sportsbooks.

Detroit vs. Buffalo Game Info

• When: Sunday, December 15, 2024 at 4:25 p.m. ET
• Where: Ford Field in Detroit, Michigan
• TV Info: CBS
• Live Stream: Watch this game on Fubo

Lions vs. Bills Betting Insights

• Detroit is 9-4-0 ATS this season.
• As 2.5-point favorites or more, the Lions are 8-4 against the spread.
• The teams have hit the over in seven of Detroit’s 13 games with a set total.
• Buffalo’s record against the spread in 2024 is 8-5-0.
• The Bills have one win ATS (1-1) as a 2.5-point underdog or greater this year.
• Of 13 Buffalo games so far this year, nine have hit the over.

Lions Player Props

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